Combining opioids and benzodiazepines can increase risk of overdose because both types of drugs can cause sedation and suppress breathing—the … Taking both drugs together increases your risk of overdosing and of dying from an overdose. More than 30% of opioid overdose deaths involve benzos. 2020 Taking opioids and benzodiazepines at the same time may cause heavy drowsiness, slow your breathing, or stop your breathing entirely. This Taking opioids and benzodiazepines at the same time, even for a short time can be dangerous because both medicines slow down the central nervous … Taking opioids and benzodiazepines at the same time may slow or stop your breathing or make you very sleepy. Learn why mixing benzodiazepines and opioids is dangerous, how it increases the risk of overdose, and where to find proper treatment. We learnt that co-using benzos or z-drugs and opioids can happen separately or simultaneously. It can be accidental or intentional. How people use benzos or z- …